As with most of the album the song was produced by Poke & Tone of Trackmasters,[1] who used a sample from Diana Ross' and Marvin Gaye's duet "Stop, Look, Listen (To Your Heart)".
[3] The track's lyrics mention several characters 50 remembers from his formative years in Queens, including Kenneth McGriff and his nephew Gerald Prince Miller of the '80s drug gang Supreme Team.
[4] It was rumored that the song and the subsequent music industry blacklisting of 50 Cent by Kenneth "Supreme" McGriff and his associates led to the murder of Run DMC's Jam Master Jay.
According to an affidavit by IRS agent Francis Mace, law enforcement officials believed that the shooting of 50 Cent in 2000 was in retaliation for the lyrics of the song which detailed the history of The Supreme Team.
[5] "Ghetto Qur'an" served as a basis for 50 Cent's rivals (mainly Ja Rule, Irv Gotti and the Murder Inc. music group, with whom he was feuding at the time) labeling him a snitch.