Ghostly Tales was part of a wave of new horror and suspense comics published by Charlton during this period.

Ghostly Tales was predominantly bimonthly during its run; it went on a publishing hiatus between issues #124 and #125 from January to August 1977.

Regular contributors to the book included Pat Boyette, Steve Ditko, Wayne Howard, Russ Jones & Bhob Stewart, and Rocke Mastroserio.

Over the course of its 18-year run, Ghostly Tales was edited by Pat Masulli, Sal Gentile, and George Wildman.

In October 1984, Charlton suspended publication, and Ghostly Tales ended its run, although the company did release several additional horror reprint issues under different titles through 1986.