The eponymous Dr. M. T. Graves was a fictional character who hosted the stories in each issue of this title, and very occasionally took part in a tale.

In issue #5, the fourth-wall-breaking story "Best of All Possible Worlds" by Steve Skeates and Jim Aparo involved a reader who's pulled into the pages of the comic book, and has to decide whether to venture back to the real world.

[6] Among the artists whose work appeared were Steve Ditko, following his falling-out with Marvel Comics; newcomer Jim Aparo, later to be one of Batman's signature artists; regular Charlton talents including Vince Alascia, Pat Boyette, Pete Morisi, Rocke Mastroserio, and Charles Nicholas; and such others as Rich Larson, Don Newton and Tom Sutton.

The cover of issue #54 (Dec. 1975) marks one of the earliest professional works of John Byrne.

[5] The Many Ghosts of Doctor Graves won the 1967 Alley Award for Best Fantasy/SF/Supernatural Title.