Ghulām Khān (Pashto/Urdu: غلام خان) is a town in North Waziristan, Khyber Pakhtunkhwa, Pakistan.

It is the third most important border crossing point between Pakistan and Afghanistan, after Chaman and Torkham.

The border reopened for trade between Pakistan and Afghanistan on 9 March 2018.

North Waziristan region including this residential town, Ghulam Khan, has a total population of 543,254 per 2017 Census of Pakistan.

This North Waziristan District location article is a stub.