Gillis Hooftman van Eyckelberg, (German: Ägidius Hauptmann; 1521 – 19 January 1581, Antwerp) was a Dutch merchant, trader, banker, and shipbuilder from the Duchy of Limburg.

Hooftman was one of richest men of his time in the prosperous city of Antwerp, the trading center of the Spanish Netherlands.

Gillis Hooftman was the son of Erken (Arnold) Arnt Hauptmann (d. 1545), a bailiff of the Lathof in the Stockem neighborhood of Eupen, and of Tryntgen (Katharina) Hoesch.

The family originated from the Rhineland, and its earlier name of Eichelberg was changed to a Limburger form, van Eyckelberg.

His business contacts reached as far as Russia, and eventually Hooftman was in a position to purchase several trading vessels.