In 1980, he became a professor of compilers and operating systems at Sapienza University of Rome and since 1990 he has been a professor of theoretical computer science in the department of computer, control and management engineering, where he has been until recently the leader of the research group on algorithm engineering.
Ausiello has contributed to several initiatives for the development of theoretical computer science in Italy and in Europe.
In 1997, with Jozef Gruska, he took part in the creation of the IFIP Technical Committee for 'Foundations of Computer Science' (IFIP-TC1) and was the first Chairman of TC1.
From 2001 to 2015 Ausiello has been Editor in Chief of the journal Theoretical Computer Science Series A (Algorithms, Automata, Complexity and Games).
[3] He is also co-Editor in Chief of the Springer series "Advanced Research in Computing and in Software Science" (ARCoSS, a subline of LNCS),[4] member of the advisory board of the "Monograph series of EATCS", member of the editorial board of the International Journal of Foundations of Computer Science, member of the editorial board of Computer Science Review.