Son of Julius Saviour, Giorgio Del Vecchio was professor of philosophy of law at the University of Ferrara (1904), Sassari (1906), Messina (1909), Bologna (1911) and Rome from 1920 to 1953.

Reinstated in teaching during the Second World War, he worked with the Century of Italy and the magazine Free Pages (publication directed by Vito Panucci).

Along with Nino Tripodi, Gioacchino Volpe, Alberto Asquini, Roberto Cantalupo, Ernesto De Marzio and Emilio Betti, he was part of the organizing committee of INSPE, an Institute of research which in the fifties and sixties was opposed to Marxist culture, promoting international conferences and publications.

Giorgio Del Vecchio, as did his German colleagues, criticized philosophical positivism, stating that the concept of law can not be derived from the observation of legal phenomena.

In this regard, his beliefs concurred with a dispute that was taking place in Germany between philosophy, sociology and general theory of law, which looked to redefine "philosophy of law"—to which Del Vecchio attributed three tasks: Del Vecchio's books are used as reference and text books in many colleges and universities.