The attribution of his works has been dubious for centuries, until his style and career was defined by the American art historian Bernard Berenson.
One of his first identified work is the Pala dei Barcaioli ("Boatmen Altarpiece") in the church of San Pietro Martire at Murano.
His only signed work is the St. Peter and St. John the Evangelist in the Pinacoteca di Brera, which shows Lombard influences, such as that of Bramantino.
Later he was also influenced by Leonardo da Vinci's style, as visible in the Christ Washing the Feet of the Apostles in the Gallerie dell'Accademia of Venice.
He also collaborated with Marco d'Oggiono for a polyptych in the church of Santa Maria della Pace in Milan, some panels of which are now in the Pinacoteca di Brera.