He was patronized by the Emperor and the court, and his talents were so highly appreciated, that he was refused a passport when he was desirous of returning to England.
He, however, with the assistance of his friend, the Duke of Saracapriolo (at the time, the Neapolitan ambassador), contrived to escape, disguised as a courier charged with dispatches.
His departure was hastened by an accident that happened to a large cameo, Alexander and Olympia, from which he had to engrave a plate for the emperor.
Among these are, The Vision of S. Catherine, after Paolo Veronese; S. Sebastian after Jusepe Ribera; Leda after Leonardo da Vinci; and lastly, the Raising of Lazarus after Sebastiano del Piombo.
Vendramini was a very accurate draughtsman, and frequently engraved from a picture without making a preparatory drawing.