He joined the "Guild of the Legnaioli" as a "forzerinario", or chest maker; then in 1433 he matriculated in the Art of Doctors and Apothecaries.
[citation needed] In 1449 on the occasion of the birth of Lorenzo de' Medici Lo Scheggia painted the Desco da parto with the Triumph of Fame now in the Metropolitan Museum of Art in New York.
[1] Lo Scheggia died in 1486 and was buried in the basilica of Santa Croce.
In the former Abbey of Vallumbrosan Order in Soffena is also preserved a fine Annunciation, while in the Accademia Gallery in Florence is the so-called Adimari Cassone, a panel with a party scene set in a city landscape in perspective, in which the Florence Baptistery is recognisable.
Alessandro Delpriori, La giovinezza dello Scheggia e una Madonna col Bambino all'alba del Rinascimento, Firenze, Frascione Arte, 2011.