He briefly worked as a doctor in Molfetta, but in 1790 he moved to Naples to teach history and geography at the Nunziatella Military School, for which, once he became commander, with the rank of lieutenant colonel, he took care of the department of physics.

In 1775 he toured Europe on behalf of the academy, visiting many seats of learning in Germany, France, England and the Netherlands and meeting naturalists and scientists.

Later he taught physics at the Medical College of the Hospital of the Incurables, a position which he had to give up when he was appointed tutor to the hereditary prince, Francesco, son of Ferdinand I of Bourbon.

[3] Thanks to his many travels, which put him in contact and correspondence with authoritative exponents of the international scientific world, he published numerous essays on various topics: not only relating to physics, but also to meteorology, in particular with the treatises on thunder (1772) and on lightning (1773), geology and zoology.

Testimony of this last discipline remains the monumental Testacea utriusque Siciliane eorumque istoria et antome tabulis aeneis, a description of the molluscs of the Kingdom of the Two Sicilies, begun with the help of his assistant Stefano Delle Chiaje, who collaborated in its publication.