Vic is constantly late in picking up and dropping off his motley crew of clientele, though it's sometimes due to his own shortcomings but often because he's tasked with enough work for an entire team of people, and each of his disabled clients require specified care.

Vic meets and develops a romantic connection with Tracy, a young woman around his age who has ALS, although their dynamic is initially adversarial.

Violent protests are taking place around Milwaukee and the films climax shows the group getting caught in the crossfires of one, though they all make it out alive.

The site's critical consensus reads: "Give Me Liberty expertly juggles resonant themes and a madcap series of events to produce a chaotic comedy with heart.

"[6] Writing in The New York Times, Manohla Dargis described Give Me Liberty as “a jolt of a movie, an anarchic deadpan comedy that evolves into a romance just around the time the story explodes…It’s irresistible,”[7] while Variety called it “a boisterous, free-wheeling joyride.”[8] Despite the films nomination for Best Editing at the Independent Spirit Awards, the editing was a frequent point of contention with critics.

wrote "It’s a pity that many of her [Lolo Spencer's] most affecting scenes are fragmented by Mikhanovsky’s tirelessly visceral editing, which is so restless that it causes some key sequences—particularly the climax—to verge on incoherence[9] The film received four Independent Spirit Award nominations, including for Best Male Lead (Galust), Best Supporting Female Actress (Spencer), Best Editing (Mikhanovsky), and Best Feature Under $500,000 (John Cassavetes Award), winning in the last category.