Species of Gliocladium are considered to have pathogenic potential although they are not commonly thought of as a disease causing agent in humans and animals.

This status has been assessed by the American Biological Safety Association based upon criteria of the Classification of Infective Microorganisms by Risk Group.

[6] Most species of Gliocladium grow rapidly in culture producing spreading colonies with a cotton-like texture, covering a Petri dish in 1 week.

[7] Gliocladium can produce conidiophores that are branching and vertically oriented, similar to the genera Verticillium, Trichoderma and Penicillium.

[7] Conidia are single-celled and cylindrical, accumulating in slime droplets at the tips of phialides that often become confluent across the apex of the entire conidiophore.