Mercedes Gloria Salguero Gross (24 September 1941 – 1 November 2015) was a Salvadoran politician, businesswoman, and one of the founders of the Nationalist Republican Alliance (ARENA).

She completed her primary and secondary school studies at the Colegio La Asunción in Santa Ana and San Salvador.

In Europe, she studied world history, geography, literature, and art in Switzerland, France, and the United Kingdom.

Further, she acted as Coordinator of the Permanent Round Table for Dialogue and Understanding during the presidential term of Elías Antonio Saca.

Salguero Gross died from cardiac arrest at a hospital in Santa Ana, El Salvador, on 1 November 2015, at the age of 74.