Glutamate synthase

Glutamate synthase (also known as Glutamine oxoglutarate aminotransferase) is an enzyme and frequently abbreviated as GOGAT.

[1][2] This is of great importance as primary productivity in many marine environments is regulated by the availability of inorganic nitrogen.

The primary sources of inorganic nitrogen used by marine algae are nitrate and ammonium.

Both forms are ultimately incorporated into amino acids through the sequential reaction of glutamine synthetase (GS) and glutamate synthase (glutamine:2-oxoglutarate aminotransferase; GOGAT).

In photosynthetic eukaryotes, GS and GOGAT isoenzymes are localized in the cytosol and chloroplast.