It was released on 7 February 2000 as the first single from their fourth studio album, Standing on the Shoulder of Giants (2000), as well as their first following the departure of rhythm guitarist Bonehead and bassist Guigsy.

The song peaked at number one on the UK Singles Chart and was later certified Gold for sales and streams exceeding 400,000.

Noel described the song as "the closest we came to sounding like a modern day Beatles" in the 'Lock the Box' interview found on the DVD in the special edition of Stop the Clocks (2006).

In the "Lock the Box" interview, Noel considers "Go Let It Out" to be "head and shoulders" above any other songs he had written during this time, and "up there with some of the best things I've ever done."

[3] It features Liam singing on a double decker bus, before disembarking it and entering a field where Noel, Gem and Alan are and performing the rest of the song there.