The goblet cell carcinoid (GCC) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.

[1] GCCs may present as appendicitis.

They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear chromatin (stippled chromatin).

GCCs have an aggressive course compared to other appendiceal neuroendocrine tumours.

[1] GCCs are treated with surgery.