[2][3] Born in Sagarejo, Bitadze started playing basketball professionally with VITA Tbilisi in the VTB United League.
"[4] As he became more involved in basketball, he began idolizing Georgian players Zaza Pachulia and Tornike Shengelia, as well as NBA stars Pau Gasol and Shaquille O'Neal.
[13] Bitadze was drawn to the club because it had produced many NBA players like Nikola Jokić and Ivica Zubac, and he thought the Serbian league was "well run.
"[15] In December 2015, Bitadze averaged 7.8 points and 4 rebounds per game to help Mega's junior team win the Torneo Città di Roma and qualify for the 2015–16 Adidas Next Generation Tournament (ANGT).
Bitadze averaged 17.7 points per game and led the tournament with 10 rebounds and 3.8 blocks per contest, en route to making the All-Tournament Team.
[27] Bitadze recorded 19 points and season bests of 15 rebounds and 6 blocks on 24 April, in a 92–90 loss to Mladost Zemun in the KLS.
In an exhibition game versus NCAA Division I team Kentucky on 11 August 2018, Bitadze suffered an injury towards the end of the first half and did not return.
[32] On 30 October, two days after recording 26 points, 10 rebounds and 3 blocks against Mornar Bar, Bitadze was named monthly MVP in the ABA League.
[33] In his following appearance on 3 November, he scored a season-high 28 points, shooting 10-of-11 from the field, while posting 11 rebounds and 4 blocks in an 81–74 loss to Partizan.
[39] On 3 January 2019, he had another strong EuroLeague performance, posting 23 points, 8 rebounds and 3 blocks off the bench in a 111–94 defeat to Olimpia Milano.
[43] On 19 June, during media availability for the draft, Bitadze appeared in a viral photo that showed him being ignored by reporters, who instead surrounded Zion Williamson, the eventual first overall pick, in the background.
[47] On 28 October 2019, Bitadze made his NBA debut, coming off the bench in a 110–99 loss to the Cleveland Cavaliers with two points and a rebound.
[51] Bitadze played for the Georgian national under-17 team at the 2015 FIBA Europe Under-16 Championship Division B, averaging 14.2 points, 8.8 rebounds and 3.7 blocks per game en route to a fifth-place finish.
[54] Bitadze returned to national team play in 2017, averaging 10.9 points and 6.3 rebounds per game at the FIBA Europe Under-20 Championship Division B.
[10] Bitadze was first named to the Georgian senior national team at EuroBasket 2017, but a calf ligament injury forced him to sit out of the entire competition.
[55] On 24 November 2017, Bitadze debuted for the senior national team versus Germany during qualification for the 2019 FIBA World Cup, scoring 4 points in 17 minutes.