Goniobranchus setoensis is a species of sea slug, a dorid nudibranch, a marine gastropod mollusc in the family Chromodorididae.

This species was known as Chromodoris setoensis for many years before it was transferred to the genus Goniobranchus on the basis of molecular (DNA) evidence in 2012.

It occurs in the central Indo-Pacific region from Japan to Sri Lanka, and as far east as the Marshall Islands and Kiribati.

The tips of the rhinophores and the outer part of the gills is white.

[5] Goniobranchus setoensis feeds on sponges of the family Aplysillidae.