The series stars Bill Bixby as Matt Cassidy, and Mariette Hartley as Jennifer Barnes: two news anchors at WYN-TV, a fictional television station in Boston, Massachusetts.

However, when Matt's ratings begin to slide, the station management pairs the reluctant anchor with female co-anchor Jennifer.

The series title comes from Matt's signoff at the end of the nightly newscasts, as "Beantown" is a common nickname for Boston (despite locals' disdain for the appellation).

[1] Co-stars included Tracey Gold as the divorced Jennifer's daughter Susan and George Coe as station manager Dick Novak.

Over the two seasons, Charles Levin, G. W. Bailey, Jim Staahl, Stephanie Faracy and Todd Susman played their co-workers at WYN.