[2] She attended the University of Colorado, where she graduated in 1920, while working for Theodore Cockerell.

Cockerell introduced Sandhouse to apiology, the study of bees.

After graduation she became a Junior Entomologist at the United States Department of Agriculture's Bureau of Entomology, working in the Division of Insect Identification.

[2] She worked there until her death, ending her career as an Associate Entomologist.

[3] Research wise, Sandhouse focused on taxonomy of Hymenoptera, specifically Apoidea.