Grand Avenue is a major east-west street in the city of Chicago and nearby DuPage County, although it deviates somewhat from Chicago's grid system, as it is diagonal west of Western Avenue.

The street runs from the Kingery Highway (also known as U.S. Route 20 and Illinois Route 83) in Elmhurst, east through the western suburbs, and then east-southeast into Chicago, through the Magnificent Mile shopping area, and continuing out to Navy Pier, where it ends.

[1] Grand Avenue was originally known as Whiskey Point Road,[2] first used as a trail by the Miami, Illini and many other Native Nations, it leads to the West Side of Chicago, near Western Avenue.

The Red Line also stops at Grand at State Street, close to the Magnificent Mile and Navy Pier.

Pace bus route 319 serves Grand Avenue in Franklin Park, Elmwood Park, and Chicago, It runs from Grand/Nordica in Chicago, to Wolf Road/North Avenue in Northlake.