The Grand Gulf Mound (22CB522) is an Early Marksville culture archaeological site located near Port Gibson in Claiborne County, Mississippi, on a bluff 1 mile (1.6 km) east of the Mississippi River, 2 miles (3.2 km) north of the mouth of the Big Black River.

[1] The site has an extant burial mound, and may have possibly had two others in the past.

Copper objects, Marksville culture ceramics and a stone platform pipe were found in excavations at the site.

Unlike some other Hopewell sites, such as the Tremper Mound in Scioto County, Ohio, the site showed no evidence of a mortuary or communal structure previous to the construction of the mound.

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