[3] From 5 to 16 October 1925, the hotel hosted the negotiations of the Locarno Treaties, that were intended to guarantee peace after the First World War.

[1] A new film festival in the Italian-speaking part of Switzerland was planned, to counter the one begun in 1932 in Venice as being too closely related to the Fascist regime.

[4] In 1946 some trees needed to be cut down to create an open-air theatre in Lugano for the screen, but local opposition meant that the film festival was moved to the garden of the Grand Hotel in Locarno.

The furniture was sold, with exception of the gigantic Murano chandelier in the hall, long considered to be the biggest in Europe.

[2][1] In 2022 the Artisa real estate group of Stefano and Alain Artioli commenced a comprehensive renovation,[2] costing 100 million Euros.