The Grand Rapids Subdivision is a railroad line in Western Michigan and Northern Indiana.

It runs 136 miles (219 km) from Porter, Indiana to Grand Rapids, Michigan.

In addition to freight traffic, the line hosts Amtrak's daily Pere Marquette.

The northern end of the line is in Grand Rapids, Michigan, where it meets the Grand Rapids Terminal Subdivision at Wyoming Yard.

The Pere Marquette Railway, successor to the Chicago and Michigan Lake Shore, extended the line south from Union Pier to Porter, Indiana, in 1903.