Alfonso Signorini, again, as presenter of the main show, with season 4 housemate Antonella Elia and the singer Pupo as opinionists.
[3] Due to this season being extended into February 2021, Grande Fratello 17, which was originally planned to air in Spring 2021, would be postponed indefinitely.
[5] On 25 January 2021, Alfonso Signorini announced that for the fourth time (and to the discouragement of the original housemates), the show would be extended by three days, with the finale happening on 1 March 2021.
[6] In the end, the show lasted 169 days, making it the longest celebrity season at the time, being later surpassed by Grande Fratello VIP 6.
On January 7, 2022, Dayane made a cameo in Grande Fratello VIP 6, visiting contestant Soleil Sorge, one of her best friends.