Grant Avenue in San Francisco, California, is one of the oldest streets in the city's Chinatown district.

[citation needed] In 1835, the very first housing structure of Yerba Buena (the later San Francisco) was erected by William A. Richardson at what today is Grant Avenue, between Clay and Washington streets.

[3] When California came under the control of the United States following the Mexican–American War of 1846–1848, the street now called Grant was named Dupont Street, in honor of a Naval admiral from the USS Portsmouth (Portsmouth Square, located one block east, was named after that ship).

In the following years, Dupont Street became the location for many Chinese stores,[4] along with some opium dens, brothels, and Tong wars.

Today, the intersection of Grant Avenue and Bush Street marks the southern entrance to Chinatown.