Less commonly, it involves shredding or grinding solid material into finer granules or pellets.

Normally, the smaller and/or denser particles tend to concentrate at the base of the container with the larger and/or less dense ones on the top.

Granules produced from such a cohesive system will be larger and more isodiametric (roughly spherical), both factors contributing to improved flow properties.

These small particles would have to be compressed very slowly for a long period of time to make a worthwhile tablet.

[1] The granulation liquid (fluid) contains a solvent or carrier material which must be volatile so that it can be removed by drying, and depending on the intended application, be non-toxic.

Therefore, water may not be strong enough to create and hold a bond.The binding of the particles together with the use of liquid is a combination of capillary and clinging forces until more permanent bonding is established.

Funicular state alteration linking the pendular and capillary where voids are not fully saturated with liquid.

The process can be very simple or very complex depending on the characteristics of the powders, the final objective of tablet making, and the equipment that is available.

[2] This continuous wet granulation technology can be carried out on a twin-screw extruder into which solid materials and water can be fed at various parts.

When a tablet press is used for dry granulation, the powders may not possess enough natural flow to feed the product uniformly into the die cavity, resulting in varying density.

In wet-granulation lines, water is continually sprayed in the cutting chamber to remove the debris and impurities, and acts as a lubricant of the steel blades; in dry-granulation lines, water is not present, but such technology generally produces output of lower quality than the wet technology.

[8] While the process is relatively simple, it must be carefully parametrized, as the high temperatures resulting from friction can damage the material and affect its plasticity.

Regular maintenance and sharpening of the scissor blades are essential, as well as close monitoring of the process due to potential clogging and jamming.

The material is molten and extruded into thin rods, which are then cooled in a water tank and finely chopped into small cylindrical pellets.