Granuloma gluteale infantum is a cutaneous condition that appears in the anogenital region of infants as a complication of diaper dermatitis.
[2] In cases of primary irritant contact dermatitis, the lesions manifest clinically as numerous asymptomatic erythematous papules and nodules in the diaper area.
[4] Contributing factors include prolonged use of fluorinated steroids,[5] and benzocaine,[6] diaper occlusion in incontinent adults and infants,[7] candidiasis,[8] and irritant contact dermatitis.
[9] The histological picture shows an underlying hyperplastic epidermis and parakeratosis, accompanied by a non-specific perivascular dermal infiltrate made up of neutrophils, histiocytes, lymphocytes, plasma cells, and eosinophils.
[10] In order to treat granuloma gluteale infantum, the diaper area needs to be kept dry and clean, and the irritant should be eliminated or lessened.