Gravity-assisted microdissection

The dissected material is allowed to fall by gravity into a cap and may thereafter be used for isolating proteins or genetic material.

[1] Two manufacturers in the world have developed their own device based on GAM method.

[citation needed] In the case of ION LMD system, after preparing sample and staining, transfer tissue on window slide.

Motorized stage moves to pre-selected drawing line and laser beam cuts the cells of interests by laser ablation.

Selected cells are collected in the tube cap which is under the slide via gravity.