Grayson is a town in Okmulgee County, Oklahoma, United States.

[4] Grayson was originally named Wildcat and was located within the area that became McIntosh County at statehood.

[5] According to the United States Census Bureau, the town has a total area of 1.1 square miles (2.8 km2), all land.

36.4% of all households were made up of individuals, and 9.1% had someone living alone who was 65 years of age or older.

There were 13.2% of families and 22.3% of the population living below the poverty line, including 9.5% of under eighteens and 43.3% of those over 64.