The Great City Synagogue (Ukrainian: Велика міська синагога, romanized: Velyka miska synahoha, Polish: Wielka Synagoga Miejska we Lwowie) was a former Orthodox Jewish synagogue in the city of Lviv (Polish: Lwów, German: Lemberg), in what is now the Lviv Oblast of Ukraine.

On 15 June 1527 a catastrophic fire destroyed parts of the city including the synagogue.

It served as the Great City Synagogue until 1797, when it was ordered for demolition, based due to its small size.

The staircase was reconstructed and a new stairway was added, leading to the women's prayer room on the gallery, completed in 1910.

[2] During World War II, on 14 August 1941, the German Nazis burned the synagogue.