The hospital works with the UCL Institute of Child Health, and is the largest centre for research into childhood illness outside the United States and Canada, and a major international trainer of doctors and nurses.

In July 2017 £24.4 million was overdue from patients based abroad, mostly in cases of sponsorship by a government or other international organisation.

It plans to continue increasing by 10% a year with “marketing road shows” in China, Russia and India.

[12] In April 2012, BBC One London broadcast a documentary called "Great Ormond Street Hospital", presented by Tim Donovan, which explained how the trust is facing accusations that it is downgrading child protection work and "victimising" staff who raise concerns.

[15] In February 2016 it emerged that the trust had not properly recorded waiting time information for patients in the outpatient, surgical and diagnostic divisions.

Consultant paediatrician Kim Holt and three colleagues wrote to Great Ormond Street Hospital managers in 2006, a year before Baby P's death warning that understaffing and poor record keeping posed a serious risk to patients' safety at St Anne's clinic in Haringey, north London.

[17] In 2014, following a BBC documentary into Baby P's case, Great Ormond Street Hospital released a statement stating they have publicly apologised for their failings and have worked since to make sure improvements were made.