The Great Western Quicksilver Mine was a mercury mine[2] in California, near Middletown in Lake County.

In 1880, Andrew Rocca was the superintendent of the Great Western Mine.

His daughter, Helen Rocca Goss, wrote that the Great Western Quicksilver Mine employed 25 white miners and about 200 Chinese, a number consistent with numbers at Sulphur Bank Mine, located adjacent to Clear Lake.

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