Great Wilne is a small village in Derbyshire, England on the border with Leicestershire.
The population at the 2011 Census is included in the civil parish of Shardlow and Great Wilne.
In 1009 Æþelræd Unræd (King Ethelred the Unready) signed a charter at the Great Council which recognised the position and boundaries of Westune.
Under this charter Æþelræd gave his minister a number of rights that made him free from tax and to his own rule within the manor.
There is archaeological evidence of a deserted medieval settlement at Church Wilne.