Gobiodon histrio, the Broad-barred goby, is a species of goby native to the Indian Ocean from the Red Sea to the western Pacific Ocean to southern Japan, Samoa and the Great Barrier Reef.

This species is a reef dweller, being found at depths of from 2 to 15 metres (6.6 to 49.2 ft).

At high enough concentrations, the toxin causes the predator to lose equilibrium and tip over.

[4][5] It takes part in a mutualistic relationship with a species of coral, Acropora nasuta.

When the coral is damaged by toxic Chlorodesmis algae, it produces a compound that attracts the fish.