[1] The square is named for Revolutionary War hero General Nathanael Greene, an aide to George Washington.

[2] A native of Rhode Island, Greene commanded Southern forces during the Revolution, and after the war settled at Mulberry Grove, an estate fourteen miles (23 km) above Savannah.

134 Houston Street, in the square's southeastern tything block, dates to the late 1800s.

[4] In the northwestern trust lot is the Second African Baptist Church, the site where Union Army general William Tecumseh Sherman announced Special Field Orders 15, better known as "40 acres and a mule".

546–548 East President Street (known as the Mary Cullum Property, now occupied by the Green Palm Inn) are two seamen's cottages, built circa 1897.