Gregory Charles Keagle (born June 28, 1971) is an American former right-handed pitcher in Major League Baseball (MLB) who played for the Detroit Tigers from 1996 to 1998.

Keagle was selected in the sixth round, 170th overall, of the 1993 Major League Baseball Draft by the San Diego Padres.

He was 11-1 with a 2.05 ERA in 14 games for the Rancho Cucamonga Quakes and was named to the California League All-Star team.

Keagle was on the Tigers' Opening Day roster in 1996, and he made his debut in their first game of the season, April 1.

He pitched three innings in his first big league game, surrendering three hits, walking two and striking out two.

Since retiring from professional baseball, Keagle has coached for the Rochester Institute of Technology (RIT) Tigers.

Greg Keagle currently resides in Pittsford, New York with his wife Danielle and their three children, Olivia, Jack, and Luke.