[3][4][5] The season is produced by ABC Studios, in association with Shondaland Production Company and Entertainment One Television; the showrunners being Krista Vernoff and William Harper.

Meredith puts her career in jeopardy when she commits insurance fraud for a father and daughter seeking asylum.

Jo continues to let her personal life affect her job after she accidentally gives Gus and his family false hope.

Maggie accepts Jackson's invitation to move in together, and Koracick finds Teddy her dream home in Seattle.

[44] On August 13, 2018, it was announced that Jeff Perry would be returning as Thatcher Grey, Meredith's father, for the first time since his last appearance in the seventh season.

[45] On September 6, 2018, it was announced that Alex Landi had been cast in a recurring role as Dr. Nico Kim, who will be the first gay male surgeon to appear on the show.

[41] On March 5, 2019, it was revealed that Abigail Spencer would reprise her role as Megan Hunt for 1 episode this season, which will air during spring.