On October 30, 2020, the series began streaming episodes weekly on Tsuburaya's Ultraman Official YouTube channel to mark the second anniversary of SSSS.Gridman.

It starred Matthew Lawrence as Sam Collins/Servo, Glen Beaudin as Malcolm Frink, Troy Slaten as Amp Ere, Kevin Castro as Tanker, Robin Mary Florence as Sydney Forrester, Rembrandt Sabelis as Lucky London, Jayme Betcher as Jennifer Doyle, John Wesley as Principal Pratchert, Diana Bellamy as Rimba Starkey, Kelli Kirkland as Yolanda Pratchert, and Tim Curry as the voice of Kilokahn.

The story revolves around a rock band named Team Samurai, led by Collins, that fights evil Mega Virus monsters created by Malcolm Frink and brought to life by Kilokahn in the Digital World.

Due to direct involvement from Tsuburaya, unlike most adaptions of Tokusatsu programs from that time period, Superhuman Samurai Syber-Squad remained largely faithful to its source material and retained elements from Gridman including sound effects, character traits and arcs, plot points, and certain names.

Takeshi Todo, a former brainwashed servant of Khan, reflects on the past incidents as monster attacks took place in real life.