In addition to students promoted from Griswold Middle School, the school also enrolls students from the nearby towns of Canterbury, Franklin, Lisbon, Norwich, Preston, Sprague, and Voluntown.

The new Griswold High School was built in 1992 adjacent to the original School, and shares Griswold Public Schools' 70-acre campus along the Quinebaug River[4] in northern New London County.

Griswold High School's state-of-the-art facility features various labs for STEM programs (Sciences, Engineering, Manufacturing, Medical, Culinary, and an advanced-technology Nexus Lab for Computer-Aided Drafting and Design, Animation, coding, and esports[5]), spacious classrooms, a modern Learning Commons library media center,[6] a 600-seat auditorium and musical rehearsal spaces, a gymnasium, print-shop, athletic fields, nature trails,[7][8] and more.

[11] Griswold High School became a member of the Eastern Connecticut Conference (ECC) in 2000, when it merged with several schools from the Quinebaug Valley Conference (QVC).

[12] The Griswold sports teams are known as the Wolverines and compete in: Griswold High School's football rivalry with Plainfield High School dates back to 1937; the Thanksgiving Day game tradition began in 1966.