The Groot Letaba River headwater streams originate in the Drakensberg Escarpment, descending in long runs with an occasional riffle or pool, mostly in the Limpopo province of South Africa.
Lower down, the Molototsi River (a seasonal stream) and Nsama River join before the Nsami Dam.
Just before the Kruger National Park the Klein Letaba River flows into the river.
More than 20 major dams have been constructed in the Groot Letaba River catchment.
This article related to a river in South Africa is a stub.