Guadalcanal (Spanish pronunciation: [ɡwaðalkaˈnal]) is a village in the province of Seville, in the autonomous community of Andalusia, Spain.

Guadalcanal is 80 kilometres north of Seville, it depends to the judicial party of Cazalla de la Sierra.

It was reconquered by the Order of Santiago in 1241 from the Moors, then Guadalcanal belonged to the Kingdom of León as well as other parts of Extremadura.

In ecclesiastical terms, it belonged to the Santa María de Tendudia vicary.

As other rural communities in Spain, it faced a massive exodus of its inhabitants to the cities in the 20th century.