[2] The fertile lands were first settled in the early 16th century, resulting in narrow parcels radiating from north to south.
Guadalupe became the centre of cereal production on the island, with the lands acquired by many of the principal families of Santa Cruz.
It is a multi-polar structure, highlighted by isolated centres that include some residences, churches, schools and impérios, while the majority of homesteads are dispersed along the roadways.
The principal localities in the parish, include: This fertility and open space made settlement and population growth rapid, especially between the end of 15th century and 1550.
With increased poverty, the population began to decrease, resulting in an exodus to the United States by the second half of the 20th century.