He is the CEO of Healr Solutions, a Senior Lecturer at MIT and a Massachusetts Rare Disease Advisory Council Member.

Born with a rare form of hemophilia in a small town in Mexico, his family often undertook an eight-hour bus journey to reach his hematologist, only to find the necessary medication unavailable.

A critical moment came when Hayes-Mota experienced a near-fatal incident due to Appendicitis, complicated by uncontrollable bleeding from his hemophilia.

[8] He was the CEO and founder of Healr Solutions, an AI-powered company optimizing drug distribution and production worldwide, which he successfully exited and sold to investors.

[10] Previously, at Biogen, Amgen and GSK he directed the manufacturing and distribution of medicines to 113 countries, providing 2.3 billion people with treatments.

[11][12][13] In 2024, the U.S. Department of Health and Human Services Secretary, Xavier Becerra, appointed Guadalupe Hayes-Mota, to serve on the Cures Acceleration Network (CAN) Review Board of the NIH to provide expert guidance on accelerating the development and delivery of medical treatments, impacting millions of lives globally.