The Guanajibo River (Spanish: Río Guanajibo) is a river that runs through Hormigueros, Cabo Rojo, Mayagüez, San Germán, and Sabana Grande in Puerto Rico.

[3][4] In mid 2018, the United States Army Corps of Engineers announced it would be undertaking a major flood control project of the river, with a $60 million budget.

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