Guangzhounan (Guangzhou South) railway station (simplified Chinese: 广州南站; traditional Chinese: 廣州南站; Jyutping: gwong2 zau1 naam4 zaam6; Cantonese Yale: Gwóngjāu Nàahm Jaahm) is located in Shibi, Panyu District, Guangzhou, Guangdong Province, China.

It is a large modern rail terminal 17 kilometres (11 mi) south of central Guangzhou.

For a brief time it was Asia's largest railway station by area when it officially started operation in early 2010.

The formation of a centralized transfer center will see connections with the future Guangzhou Metro Line 20.

[9] Panyu railway station operated by Guangdong Intercity starts operation since 26 May 2024,[10][11] while for transferring between Guangzhou South Railway Station and Panyu railway station, no internal transfer walkway was available meaning that an external transfer,[11] involving "exit-and-enter" at two different gates, together with a security check[12] conducted in-between, is required.