Part of the Metekel Zone, Guba is bordered by the Abay River on the south which separates it from the Kamashi Zone, Sudan on the west, Amhara Region on the north, Dangur on the east, and on the southeast by the Beles River, which separates it from Wenbera.
[2] Based on figures from the Central Statistical Agency in 2005, this woreda has an estimated total population of 10,851, of whom 5,305 are men and 5,546 are women; 1,255 or 11.57% of the population are urban dwellers which is greater than the Zone average of 10.7%.
The four largest ethnic groups reported in Guba were the Gumuz (66.5%), the Shinasha (24.9%), the Amhara (6.6%), the Awi (1%) a subgroup of the Agaw, and the Tigrayans (1%).
The majority of the inhabitants were Muslim, with 88.9% of the population reporting that they held that belief, while 7% practiced Ethiopian Orthodox Christianity.
Concerning education, 9.5% of the population were considered literate, which is less than the Zone average of 18.61%; 5.67% of children aged 7–12 were in primary school; a negligible number of the children aged 13–14 were in junior secondary school; and a negligible number of the inhabitants aged 15–18 were in senior secondary school.