Guelmim-Oued Noun (Arabic: ڭلميم-وادي نون, romanized: gulmīm wādī nūn) is one of the twelve regions of Morocco.

[4] Guelmim-Oued Noun borders the regions of Souss-Massa to the northeast and Laâyoune-Sakia El Hamra to the south.

It borders Algeria's Tindouf Province to the east and Mauritania's Tiris Zemmour Region to the southeast.

[5] The region is bisected by the usually dry lower course of the Draa River which runs east to west.

[8] Guelmim-Oued Noun comprises four provinces:[4] Fishing is an important economic activity: there are ports at Sidi Ifni and at El Ouatia.