Their breast and belly are grayish brown to olive-brown with bold, blackish-edged, pale buff to creamy white streaks.

Juveniles have darker upperparts than adults, a grayer crown with more obvious spots, and whiter, somewhat reduced, streaks on the underparts.

[7] The Guinana woodcreeper is found in northern Amazonia in the eastern Venezuelan states of Delta Amacuro and Bolívar, the Guianas, and northern Brazil north of the Amazon River from the Rio Negro east to the Atlantic ocean.

It hitches along branches, often on their underside, mostly in the forest's sub-canopy and canopy, occasionally in the middle levels, and rarely if ever in the understory.

Only one nest is known; it was in a cavity near the top of a dead stump and was lined with bark chips.

The Guianan woodcreeper's song is "a soft trill...that rises and falls in pitch, and trails off at end, comprising a series of 20–40 notes and lasts c. 2–3 seconds".

[1] Because it is primarily a canopy specialist it is not well known; it is thought to be uncommon to fairly common throughout its range.